The Global Biological Standards Institute (GBSI), a non-profit organization dedicated to enhancing the quality of biomedical research by advocating best practices and standards, is seeking the views of researchers on cell culture and authentication as well as research antibodies. We have agreed to help GBSI distribute surveys on these topics through this link:
The purpose is to gather valuable information about how researchers view the best practices in each of these areas and what they see as the challenges and barriers to implementing those practices. GBSI will be analyzing the data and publishing the results later in 2015.
Cells are repeatedly cultured, frozen, and passaged, and procedures to handle cells vary dramatically between laboratories. As a result, misidentification (cross-contamination), microbial contamination, and labeling and other errors can and do occur. Misidentification of cell lines can be prevented by periodic cell authentication such as through DNA profiling.
The use of misidentified, mischaracterized, or contaminated monoclonal and polyclonal antibodies—often purchased from commercial vendors—is an equally vexing problem. Assay-specific validation of antibodies can help researchers translate bench discoveries into FDA-approved diagnostics and therapies
At the beginning of the survey (question #3), you will notice that there is a simple way to choose to take one or both surveys depending on your interests. GBSI’s pre-testing indicates that each survey can be completed in as little as 10 minutes. This survey will close on May 22, 2015.
Please contact Mark Gibson at GBSI, firstname.lastname@example.org if you have specific questions about the survey instrument.