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This week in Science |
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This Week in Science
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Research highlights from the current issue of Science Magazine
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Vaginal Gel Versus HIV
HIV prevention technologies for women are urgently needed, especially in sub-Saharan Africa where young women bear the greatest burden of the HIV epidemic. Abdool Karim et al. (p. 1168; published … [Read more]
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Antimalarial Drug Candidate
Spiroindolones were discovered as promising antimalarial drug candidates through a high-throughput screening approach that should be applicable to a range of neglected infectious diseases. Rottmann et al. (p. 1175; see … [Read more]
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Icy Adsorption
The highly mobile nature of adsorbed liquid water on surfaces has made structural studies using atomic force microscopy challenging, especially for the first adsorbed layer. Moreover, scanning probe methods are … [Read more]
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Free Falling Vortices
When a vessel containing a superfluid is set in rotational motion, the superfluid does not rotate uniformly with it; instead, quantized vortices develop. Vortices have been observed in a range … [Read more]
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Join the Club
An important question for policy-makers is how to communicate information (for example, about public health interventions) and promote behavior change most effectively across a population. The structure of a social … [Read more]
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From Simplicity to Complexity
The relatively simple properties of isolated electrons become rich and complex when the particle-particle interactions are strong enough to form a correlated system. Emergence of complex behavior from relatively simple … [Read more]
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Sea of Plastic
Plastics are highly resistant to degradation and persist in the environment after being discarded. Notoriously, plastics accumulate within ocean gyres, where patterns of surface circulation concentrate them into specific regions. … [Read more]
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Skin Reaction
Lymphocytes in the skin known as γδ T cells provide an important barrier against infection and injury. Unlike classical αβ T cells, less is known about the molecular requirements of … [Read more]
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Cosmic Fullerenes
Since the discovery of the buckminsterfullerene C60 in laboratory experiments, it has been speculated that fullerenes could form abundantly in carbon-rich evolved stars and, because of their stability, survive the … [Read more]
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No Guide to the Future
Although fossils can provide glimpses of evolution, the accuracy for predictions made on the basis of commonality among geographically and hierarchically distinct taxa is unknown. Alroy (p. 1191; see the … [Read more]
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Gee-Up, NEDD8
Diverse bacterial pathogens, such as Burkholderia pseudomallei and enteropathogenic Escherichia coli (EPEC), inject effector proteins into eukaryotic host cells to subvert host cell biology. Cui et al. (p. 1215; published … [Read more]
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Regulation of Energy Homeostasis
The mammalian AMP-activated protein kinase (AMPK) is a serine/threonine kinase complex that regulates cellular energy homeostasis. However, the mechanisms by which AMPK mediates transcriptional responses to metabolic perturbations has been … [Read more]
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Here to Stay
For systemic infection, bacterial pathogens must breach the mucosal epithelial barrier. Our bodies have developed a variety of strategies to protect the mucosa, including rapid turnover of epithelial cells. Muenzner … [Read more]
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