News & Press: ISAC News

The Anatomy of Single Cell Mass Cytometry Data in this Month's Cytometry Part A

Wednesday, March 6, 2019   (0 Comments)
In this issue:
Shared Resource Laboratory (SRL) Communications—A New Journal Article Type  

We announce a new publication format called the “SRL Communication” that will provide a vehicle for Shared Resource Laboratory (SRL)focused subjects to be published and disseminated to the wider scientific community. See Editorial by Derek Davie, Andrew Filby and Joanne Lannigan.

The anatomy of single cell mass cytometry data (review)

Mass cytometry was commercially released ten years ago. In this article, the authors discuss how to understand mass cytometry data for more efficient analysis of these complex data sets. See review by Olsen et al. in this issue.

Improving Quality, Reproducibility, and Usability of FRETBased Tension Sensors (original article)

Förster resonance energy transfer (FRET)-based tension sensors are emerging as useful tools because they enable the measurement of molecular-scale forces across proteins based on changes in emitted light. However, guidelines for ensuring the reliability of measurements made with these sensors have not been clearly established. In this work, we present numerical methods to improve the accuracy of FRET-based tension sensor measurements and examine the uncertainty of these measurements. See Gates et al.