Matthew Linden

Matthew Linden

Associate Professor of Haematology

Education BSc Hons PhD W.Aust I earned my PhD in haematology from The University of Western Australia in 2003 and joined the Centre for Platelet Function Studies at The University of Massachusetts Medical School (now the Centre for Platelet Research and Harvard Medical School) initially as a postdoctoral fellow and then research instructor. In 2007 I returned to Australia as an academic at RMIT University in Melbourne, where I launched the RMIT Flow Cytometry core facility in 2009. In 2012 I was recruited to the University of Western Australia as academic head of the cytometry core at the Centre for Microscopy, Charactisation and Analysis (a node of the National Microscopy and Microanalysis Research Facility). In 2015 I took up an associate professorship of haematology at the same institution in order to develop postgraduate haematology coursework and progress research on platelets systems biology.

Scientific Interest and Avenues for Collaboration I am a highly motivated and well-rounded academic with a passion for cytometry. I hold significant roles spanning teaching, research, and leadership of cytometry in Australia. Working at the interface of the shared resource laboratory, discovery, and translational research, I have developed novel cytometry techniques for the measurement of blood platelets and employed these in the development of new antiplatelet therapies. I am committed to advancing cytometry through strong, sustainable shared resource laboratories and cutting edge research. Through participation in the ISAC Scholar program, I seek to expand across research, education, and leadership of cytometry at an international level. My research focuses on two main fields: advancing understanding of blood platelets in health and disease (funded by the National Health and Medical Research Council of Australia) and advancement and development of cytometry tools for cell biology (funded by the Australian Research Council Discovery Grants Program). I have developed widely adopted flow cytometric methods for the laboratory monitoring of antiplatelet therapy, applied these to develop novel approaches to inhibition of platelet function, and extended this research and developed cytometric methods for measuring the interaction of platelets with immune cells. I also develop novel flow, imaging, and mass cytometry approaches, which broadly underpin research in other areas of biological and medical sciences.

Participation / Support of ISAC I was chair the 38th Annual Scientific Meeting of the Australasian Cytometry Society (ACS) (the Australian affiliate of ISAC), which I hosted in Perth in 2015. I am treasurer of CYTO ASIA, a joint meeting of the ACS, ISAC and Singaporean Society for Immunology, which will be held in Singapore in October 2017. I continue to be an active member of ISAC and seek to represent cytometry interests in the rapidly expanding Australasian region. I sit on the membership services committee and continue to expand my involvement in ISAC through the Scholar’s program. In 2017 I submitted an abstract for consideration at CYTO, characterizing platelet-induced signal transduction in metastatic breast cancer cells using mass cytometry.