Matthew DiSalvo
Matthew DiSalvo

Biomedical Engineer

National Institute of Standards and Technology, Maryland, USA


Education
Ph.D., Biomedical Engineering, University of North Carolina at Chapel Hill
Bachelor of Science, Biological Engineering, Cornell University

I’m a biomedical engineer specializing in bioanalytical microdevices, particularly optofluidics such as flow cytometers, microarrays, and droplet microfluidics. I have a passion for automation, and I believe that automating microfluidics is the key to achieving higher impact and to enabling commercialization. 

Scientific Interest and Avenues for Collaboration
My research in flow cytometry focuses on fundamental metrology challenges such as uncertainty quantification (UQ) and measurement comparability. I create microfluidic serial flow cytometers that replicate optical measurements on particles for direct UQ on a per-particle¬basis. UQ enables objective optimization of the operation and design of flow cytometers and has already allowed us to improve and take advantage of novel flow focusing and integrated optics in our cytometers. Also, the full time-trace data from cytometer photodetectors can be incredibly information-rich, and I am investigating new methods for their analysis and storage. I hope these technologies will catalyze additional advancements within the flow cytometry community, and I am excited to explore new applications, such as using serial cytometers or analyses to evaluate and compare the measurement performance of emerging instrumentation and software.

Participation / Support of ISAC 
Member of ISAC
CYTO 2020 Poster Presentation
CYTO 2021 Poster Presentation
CYTO 2022 Poster Presentation
CYTO 2023 Oral Presentation
CYTO 2024 Oral Presentation

Website
More information about my work is available here.